Software and Computational Systems

The Challenge Eukaryotic chromosomes possess an intricate 3D structure that helps control gene expressions by bringing in close spatial proximity genes with regulatory elements and by organizing chromosomes into compartments and domains. In recent years, we saw the advancement of a new set of techniques to capture the spatial arrangement of chromosomes including Hi-C, ChIA-PET […]

Behaviour Data Engineering and UEBA Cybersecurity  Overview  Behaviour Data Engineering plays an important role in intelligence creation under the fourth paradigm, the data-intensive scientific discovery. By collecting, aggregating, and analysing behaviour patterns of an entity (including human, things, events, …, etc.) together, deeper insights, from correlation to causations, can be possible through domain knowledge driven […]

Overview Our team delivers novel methodologies and computational algorithms for data-driven modelling with a focus on the forecasting, prediction and extreme modeling.  The team has a proven record of achievement with numerous high quality publications including 93 journal papers from 2010 to early 2016 (of which 26 are A* ranked and 25 are A ranked […]

Strategy  For an increasing number of usage scenarios, data analytics and machine learning demonstrate effectiveness in handling real-world tasks with little human involvement. The demand for constructing such kinds of systems rises rapidly but the actual construction of such a system requires lots of effort. It is not only because such systems are often data […]

Versus is a web-based application that allows experimenters to create multiple experiments based on a full 2AFC methodology (two alternative forced-choice). Participants are presented two images side-by-side, and — without imposing a time constraint — they are now asked to choose one of the two images. The preliminary result of the experiment should be a […]

Visual analysis of time-series data on protein phosphorylation presents a particular challenge: Bioinformatics tools currently available for visualising ‘omics’ data in time series have been developed primarily to study gene expression, and cannot easily be adopted to phosphorylation data, where a single protein typically has multiple phosphosites. Minardo is a novel layout strategy — a reference to Charles […]

Provenance Management Overview Provenance refers to the chain of successive custody—including sources and operations of resources such as hardware, software, documents, databases, data, and other entities. It is also concerned with the original sources of any subsequent changes or other treatment of information and resources throughout the life cycle of data. That information may be […]

Enabling the next generation of computational research in the chemical, physical and materials sciences.

Integrated water system modeling is a reasonable approach to provide scientific understanding to tackle the severe water crisis faced all over the world and to promote the implementation of integrated river basin management. After carefully evaluating the issues in the existing models, we proposed an integrated water system model by considering hydrological and biogeochemical processes, […]