Multi-omic, predictive modelling and purpose-built microbiomes

Multi-omic is the combined analysis of genomics (DNA), transcriptomics (RNA), proteomics (protein) and metabolomics (metabolite) in a single biological sample. Recent advances have made these analyses affordable and able to be performed from small amounts of sample. From these analyses, MOSH researchers can tell what microbes are present (structure of the community of microbes), what is happening and what is making it happen (the role of the microbes in the community known as community function). This information is used to identify key individuals used for a specialised function, such as, which individual microbes in a soil community plays a role in the breakdown of persistent chemicals in the environment. This can be used to model predictive outcomes of deliberate intervention and used to design a beneficial, purpose-built microbiome.