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Flow Chemistry Organic Synthesis

Organic Chemistry:

  • “The Direct α-C(sp3)-H Functionalization of N-aryl Tetrahydroisoquinolines via an Iron-Catalyzed Aerobic Nitro-Mannich Reaction and Continuous Flow Processing” M. Brzozowski, J. Forni, G. P. Savage and A. Polyzos, Chem. Commun. (2015), 51, 334-337.
  • “Flow Synthesis of Tricyclic Spiropiperidines as Building Blocks for the Histrionicotoxin Family of Alkaloids”, M. Brasholz, B. A. Johnson, J. M. Macdonald, A. Polyzos, J. Tsanaktsidis, S. Saubern, A. B. Holmes, and J. H. Ryan, Tetrahedron, 2010, 66, 6445-6449, doi:10.1016/j.tet.2010.04.092.
  • “Diels-Alder reactions of myrcene using intensified continuous-flow reactors”, Christian Hornung, Miguel Alvarez-Dieguez, Thomas Kohl, John Tsanaktsidis, 2017, Beilsten J. Org. Chem. 13, 120-126
  • “Amination of aryl halides and esters using intensified continuous flow processing”, Thomas Kohl, Christian Hornung, John Tsanaktsidis, Molecules, 2015, 20, 17860-17871
  • “Fukuyama Reduction and Integrated Thioesterification/Fukuyama Reduction of Thioesters and Acyl Chlorides Using Continuous Flow.” Asadi, M.; Bonke, S.; Polyzos, A.; Lupton, D. W., ACS Catal. 2014, 4, 2070-2074
  • “Porous Double-Layer Polymer Tubing for the Potential Use in Heterogeneous Continuous Flow Reactions”, Herwig, G.; Hornung, C. H.; Peeters, G.; Ebdon, N.; Savage, G. P., ACS Appl. Mater. Interfaces 2014, 6, 22838-22846.
  • “A Two Stage, Continuous-Flow Synthesis of Spirooxazine Photochromic Dyes”, Mark York, Adriana Edenharter,  J. Chem., 2012, 66, 172–177, doi:10.1071/CH12435.