Paper: Deep learning based HEp-2 image classification: A comprehensive review
Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent years, amongst which deep learning based methods have shown impressive performance.
This paper provides a comprehensive review of the existing deep learning based HEp-2 cell image classification methods. These methods perform HEp-2 image classification at two levels, namely, cell-level and specimen-level. Both levels are covered in this review.
At each level, the methods are organized with a deep network usage based taxonomy. The core idea, notable achievements, and key strengths and weaknesses of each method are critically analyzed. Furthermore, a concise review of the existing HEp-2 datasets that are commonly used in the literature is given.
The paper ends with a discussion on novel opportunities and future research directions in this field. It is hoped that this paper would provide readers with a thorough reference of this novel, challenging, and thriving field.
Fig. 13. Sample categories available in existing HEp-2 public cell image datasets.
S. Rahman, L. Wang, C. Sun, and L. Zhou, Deep learning for HEp-2 image classification: A comprehensive review, Medical Image Analysis, 65:101764, October 2020.
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